E2F6 Antibody - middle region
Catalog Number:
ASB-ARP32221_P050
- Images (3)
| Article Name: | E2F6 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP32221_P050 |
| Supplier Catalog Number: | ARP32221_P050 |
| Alternative Catalog Number: | ASB-ARP32221_P050-25UL,ASB-ARP32221_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human E2F6 |
| Alternative Names: | E2F-6 |
| E2F6 encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. |
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Human Lung |
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WB Suggested Anti-E2F6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: HepG2 cell lysateE2F6 is supported by BioGPS gene expression data to be expressed in HepG2 |
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E2F6 antibody - middle region (ARP32221_P050) in Human HepG2 using Western Blot |
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