E2F6 Antibody - middle region

Catalog Number: ASB-ARP32221_T100
Article Name: E2F6 Antibody - middle region
Biozol Catalog Number: ASB-ARP32221_T100
Supplier Catalog Number: ARP32221_T100
Alternative Catalog Number: ASB-ARP32221_T100-25UL,ASB-ARP32221_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human E2F6
Alternative Names: E2F-6
E2F6 is a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants encoding several different isoforms have been found for this gene.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 14kDa
NCBI: 1876
UniProt: Q6Q9Z5
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-E2F6 antibody
Catalog Number: ARP32221_T100
Paraffin Embedded Tissue: Human Lung cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
WB Suggested Anti-E2F6 Antibody
Titration: 1.25 ug/ml
Positive Control: HepG2 Whole CellE2F6 is supported by BioGPS gene expression data to be expressed in HepG2
E2F6 antibody - middle region (ARP32221_T100) in Human HepG2 using Western Blot