Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat, Yeast
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human NCOR1
Alternative Names:
N-CoR, TRAC1, N-CoR1, hN-CoR, PPP1R109
NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.