PAX7 Antibody - C-terminal region

Catalog Number: ASB-ARP32742_P050
Article Name: PAX7 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP32742_P050
Supplier Catalog Number: ARP32742_P050
Alternative Catalog Number: ASB-ARP32742_P050-25UL,ASB-ARP32742_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of PAX7
Alternative Names: HUP1, RMS2, PAX7B, MYOSCO
PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 57kDa
NCBI: 5081
UniProt: P23759
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Host: Rabbit
Target Name: PAX7
Sample Type: Fetal heart lysates
Antibody Dilution: 1.0ug/ml
Surface Plasmon Resonance Kinetic Characterization of Polyclonal Antibody Affinity. Purified polyclonal antibodies were immobilized on a Protein A/G coated Carterra LSA sensor chip (PAGH200M) at concentrations of 5, and 50 ug/mL in duplicate. Antibodies on the surface were exposed to interaction with peptides sequentially via microfluidic controlled flow at 333nM peptide concentration for kinetic characterization of the binders for affinity and specificity, followed by curve fitting using the Kinetics software. Kd determinations for both concentrations were averaged and results and standard deviation are shown.
PAX7 Antibody - C-terminal region (ARP32742_P050) in Human Fetal heart using Western Blot