DBI Antibody - N-terminal region

Catalog Number: ASB-ARP32803_P050
Article Name: DBI Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP32803_P050
Supplier Catalog Number: ARP32803_P050
Alternative Catalog Number: ASB-ARP32803_P050-25UL,ASB-ARP32803_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Human
Alternative Names: EP, ACBP, ACBD1, CCK-RP
DBI is diazepam binding inhibitor. The protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. DBI is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 12kDa
NCBI: 1622
UniProt: B8ZWD2
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-DBI Antibody
Catalog Number: ARP32803_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-DBI Antibody
Titration: 1.0 ug/ml
Positive Control: HT1080 Whole Cell
DBI antibody - N-terminal region (ARP32803_P050) in Human HT1080 using Western Blot