RFXAP Antibody - middle region

Catalog Number: ASB-ARP33226_P050
Article Name: RFXAP Antibody - middle region
Biozol Catalog Number: ASB-ARP33226_P050
Supplier Catalog Number: ARP33226_P050
Alternative Catalog Number: ASB-ARP33226_P050-25UL,ASB-ARP33226_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Guinea pig, Human
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RFXAP
RFXAP is part of the RFX complex that binds to the X-box of MHC II promoters.Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 28kDa
NCBI: 5994
UniProt: O00287
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-RFXAP Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Pancreas
RFXAP antibody - middle region (ARP33226_P050) in Human Pancreas using Western Blot