PRDM16 Antibody - middle region
Catalog Number:
ASB-ARP33260_P050
- Images (2)
| Article Name: | PRDM16 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP33260_P050 |
| Supplier Catalog Number: | ARP33260_P050 |
| Alternative Catalog Number: | ASB-ARP33260_P050-25UL,ASB-ARP33260_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Equine, Guinea pig, Human, Porcine, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human PRDM16 |
| Alternative Names: | MEL1, KMT8F, LVNC8, PFM13, CMD1LL |
| The reciprocal translocation t(1,3)(p36,q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
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WB Suggested Anti-PRDM16 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: HepG2 cell lysate |
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PRDM16 antibody - middle region (ARP33260_P050) in Human HepG2 using Western Blot |
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