BCL11B Antibody - middle region

Catalog Number: ASB-ARP33293_P050
Article Name: BCL11B Antibody - middle region
Biozol Catalog Number: ASB-ARP33293_P050
Supplier Catalog Number: ARP33293_P050
Alternative Catalog Number: ASB-ARP33293_P050-25UL,ASB-ARP33293_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BCL11B
Alternative Names: ATL1, RIT1, CTIP2, IMD49, CTIP-2, IDDFSTA, ZNF856B, ATL1-beta, ATL1-alpha, ATL1-delta, ATL1-gamma, hRIT1-alpha
BCL11B is the tumor-suppressor protein involved in T-cell lymphomas. BCL11B may function on the P53-signaling pathway. BCL11B may be a key regulator of both differentiation and survival during thymocyte development. BCL11B repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 88kDa
NCBI: 64919
UniProt: Q9C0K0-2
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Thymus
WB Suggested Anti-BCL11B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: THP-1 cell lysate
BCL11B antibody - middle region (ARP33293_P050) in Human THP-1 using Western Blot