RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5-region of the RUNX1 gene fused to the 3-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-RUNX1T1 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell lysateThere is BioGPS gene expression data showing that RUNX1T1 is expressed in HepG2
Host: Rabbit Target Name: WT1 Sample Type: 721_B Antibody Dilution: 1.0ug/mlRUNX1T1 is supported by BioGPS gene expression data to be expressed in 721_B
RUNX1T1 antibody - middle region (ARP33996_T100) in Human HepG2 using Western Blot
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