LIN28 Antibody - N-terminal region

Catalog Number: ASB-ARP34477_P050
Article Name: LIN28 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP34477_P050
Supplier Catalog Number: ARP34477_P050
Alternative Catalog Number: ASB-ARP34477_P050-25UL,ASB-ARP34477_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Goat, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep, Yeast
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LIN28
Alternative Names: CSDD1, LIN28, LIN-28, ZCCHC1, lin-28A
LIN28 acts as a translational enhancer, driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 23kDa
NCBI: 79727
UniProt: Q9H9Z2
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunohistochemistry with Human Testis lysate tissue at an antibody concentration of 5.0ug/ml using anti-LIN28 antibody (ARP34477_P050)
WB Suggested Anti-LIN28 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysate
LIN28 antibody - N-terminal region (ARP34477_P050) in Human HeLa using Western Blot