DMTF1 Antibody - middle region
Catalog Number:
ASB-ARP34828_P050
- Images (3)
| Article Name: | DMTF1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP34828_P050 |
| Supplier Catalog Number: | ARP34828_P050 |
| Alternative Catalog Number: | ASB-ARP34828_P050-25UL,ASB-ARP34828_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human DMTF1 |
| Alternative Names: | DMP1, DMTF, MRUL, hDMP1 |
| This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |
|
|
WB Suggested Anti-DMTF1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: HT1080 cell lysate |
|
|
Host: Mouse Target Name: DMTF1 Sample Tissue: Mouse Kidney Antibody Dilution: 1ug/ml |
|
|
DMTF1 antibody - middle region (ARP34828_P050) in Human HT1080 using Western Blot |
Product Guarantee and Expert Support
