KCNQ4 Antibody - middle region
Catalog Number:
ASB-ARP35148_P050
- Images (3)
| Article Name: | KCNQ4 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP35148_P050 |
| Supplier Catalog Number: | ARP35148_P050 |
| Alternative Catalog Number: | ASB-ARP35148_P050-25UL,ASB-ARP35148_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human KCNQ4 |
| Alternative Names: | DFNA2, KV7.4, DFNA2A |
| The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. |
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WB Suggested Anti-KCNQ4 Antibody Titration: 0.2-1 ug/ml Positive Control: HT1080 cell lysate |
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Lanes: 100 ug CHO cell lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Goat anti-rabbit HRP Secondary Antibody Dilution: 1:25000 Gene Name: KCNQ4 Submitted by: Anonymous |
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KCNQ4 antibody - middle region (ARP35148_P050) in Human HT1080 using Western Blot |
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