KCNA10 Antibody - N-terminal region

Catalog Number: ASB-ARP35177_P050
Article Name: KCNA10 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP35177_P050
Supplier Catalog Number: ARP35177_P050
Alternative Catalog Number: ASB-ARP35177_P050-25UL,ASB-ARP35177_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNA10
Alternative Names: Kcn1, Kv1.8
KCNA10 is a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1.Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 58kDa
NCBI: 3744
UniProt: Q16322
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Anti-KCNA10 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. KCNA10 Antibody ARP35177_P050 concentration 5 ug/ml.
WB Suggested Anti-KCNA10 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate
KCNA10 antibody - N-terminal region (ARP35177_P050) in Human HepG2 using Western Blot