STAT6 Antibody - C-terminal region
Catalog Number:
ASB-ARP38257_P050
- Images (3)
| Article Name: | STAT6 Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-ARP38257_P050 |
| Supplier Catalog Number: | ARP38257_P050 |
| Alternative Catalog Number: | ASB-ARP38257_P050-25UL,ASB-ARP38257_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human STAT6 |
| Alternative Names: | STAT6B, STAT6C, D12S1644, IL-4-STAT |
| STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. |
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STAT6 antibody - C-terminal region (ARP38257_P050) Catalog Number: ARP38257_P050 Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue Observed Staining: Cytoplasm of pneumocytes Primary Antibody Concentration: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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WB Suggested Anti-STAT6 Antibody Titration: 0.2-1 ug/ml Positive Control: recombinant STAT6 protein |
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STAT6 antibody - C-terminal region (ARP38257_P050) in recombinant STAT6 protein using Western Blot |
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