RNF14 Antibody - C-terminal region

Catalog Number: ASB-ARP38448_T100
Article Name: RNF14 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP38448_T100
Supplier Catalog Number: ARP38448_T100
Alternative Catalog Number: ASB-ARP38448_T100-25UL,ASB-ARP38448_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Human, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF14
Alternative Names: ARA54, HFB30, TRIAD2, HRIHFB2038
RNF14 contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 52kDa
NCBI: 9604
UniProt: Q9UBS8
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human kidney
WB Suggested Anti-RNF14 Antibody Titration: 2.5ug/ml
Positive Control: Jurkat cell lysate
RNF14 antibody - C-terminal region (ARP38448_T100) in Human Jurkat using Western Blot