GSCL Antibody - C-terminal region

Catalog Number: ASB-ARP38599_T100
Article Name: GSCL Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP38599_T100
Supplier Catalog Number: ARP38599_T100
Alternative Catalog Number: ASB-ARP38599_T100-25UL,ASB-ARP38599_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GSCL
Alternative Names: GSCL
Goosecoidlike (GSCL) resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology.Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 22kDa
NCBI: 2928
UniProt: O15499
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human kidney
WB Suggested Anti-GSCL Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate
GSCL antibody - C-terminal region (ARP38599_T100) in Human HepG2 using Western Blot