The immunogen is a synthetic peptide directed towards the C terminal region of human NR1H3
Alternative Names:
LXRA, LXR-a, RLD-1
Interaction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis.
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The peptide is also present in a 28 kDa isoform.
NR1H3 antibody - C-terminal region (ARP38670_P050) in Mouse Testis using Western Blot
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