Six1 Antibody - N-terminal region
Catalog Number:
ASB-ARP38717_P050
- Images (3)
| Article Name: | Six1 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP38717_P050 |
| Supplier Catalog Number: | ARP38717_P050 |
| Alternative Catalog Number: | ASB-ARP38717_P050-25UL,ASB-ARP38717_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish |
| Alternative Names: | BB138287 |
| Six1 is a transcription factor that is involved in regulation of organogenesis. It seems to be required for development of kidney, muscle and inner ear and to be involved in later steps of myogenic differentiation. It may be involved in limb tendon and ligament development. It binds a 5-TCA[AG][AG]TTNC-3 motif present in the MEF3 element in the myogenin promoter. It is thought to be regulated by association with Dach and Eya proteins. Six1 acts as activator of the IGFBP5 promoter, probably coactivated by EYA2. Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 phosphatase to the SIX1-DACH1 complex. During myogenesis, Six1 seems to act together with EYA2 and DACH2 . |
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Rabbit Anti-Six1 Antibody Catalog Number: ARP38717_P050 Formalin Fixed Paraffin Embedded Tissue: Human Adult heart Observed Staining: Cytoplasmic,Nuclear (very rare in Nuclear) Primary Antibody Concentration: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 a€'' 2.0 sec Protocol located in Reviews and Data. |
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WB Suggested Anti-Six1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Kidney |
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Six1 antibody - N-terminal region (ARP38717_P050) in Mouse Kidney using Western Blot |
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