OPTN Antibody - N-terminal region
Catalog Number:
ASB-ARP39525_P050
- Images (3)
| Article Name: | OPTN Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP39525_P050 |
| Supplier Catalog Number: | ARP39525_P050 |
| Alternative Catalog Number: | ASB-ARP39525_P050-25UL,ASB-ARP39525_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human OPTN |
| Alternative Names: | NRP, FIP2, HIP7, HYPL, ALS12, GLC1E, TFIIIA-INTP |
| OPTN is the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. |
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Rabbit Anti-OPTN Antibody Catalog Number: ARP39525_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: N/A Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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WB Suggested Anti-OPTN Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Transfected 293T |
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OPTN antibody - N-terminal region (ARP39525_P050) in Transfected 293T using Western Blot |
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