Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat, Yeast, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human U2AF2
Alternative Names:
U2AF65
U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 is the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly.