CARS Antibody - C-terminal region

Catalog Number: ASB-ARP40295_P050
Article Name: CARS Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP40295_P050
Supplier Catalog Number: ARP40295_P050
Alternative Catalog Number: ASB-ARP40295_P050-25UL,ASB-ARP40295_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Yeast, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CARS
Alternative Names: CARS, MDBH, CYSRS, MCDDBH, MGC:11246
CARS is a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 81kDa
NCBI: 833
UniProt: P49589
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-CARS Antibody
Catalog Number: ARP40295
Paraffin Embedded Tissue: Human Lung
Cellular Data: Alveolar cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
WB Suggested Anti-CARS Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
CARS antibody - C-terminal region (ARP40295_P050) in Human HepG2 using Western Blot