The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B4
Alternative Names:
AFD1, Hsh49, SAP49, SF3b49
SF3B4 is one of four subunits of the splicing factor 3B. The protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
WB Suggested Anti-SF3B4 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell lysateSF3B4 is supported by BioGPS gene expression data to be expressed in HepG2
SF3B4 antibody - N-terminal region (ARP40609_T100) in Human HepG2 using Western Blot
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