Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rat, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B1
Alternative Names:
MDS, PRP10, Hsh155, PRPF10, SAP155, SF3b155
SF3B1 is subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the introns branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures.
WB Suggested Anti-SF3B1 Antibody Titration: 0.3125ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysateSF3B1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
SF3B1 antibody - N-terminal region (ARP40733_T100) in Human Jurkat using Western Blot
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