SF3B1 Antibody - N-terminal region

Catalog Number: ASB-ARP40733_T100
Article Name: SF3B1 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP40733_T100
Supplier Catalog Number: ARP40733_T100
Alternative Catalog Number: ASB-ARP40733_T100-25UL,ASB-ARP40733_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B1
Alternative Names: MDS, PRP10, Hsh155, PRPF10, SAP155, SF3b155
SF3B1 is subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the introns branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 87kDa
NCBI: 23451
UniProt: Q7Z497
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-SF3B1 Antibody
Catalog Number: ARP40733_T100
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-SF3B1 Antibody Titration: 0.3125ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysateSF3B1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
SF3B1 antibody - N-terminal region (ARP40733_T100) in Human Jurkat using Western Blot