PUF60 Antibody - C-terminal region

Catalog Number: ASB-ARP40759_T100
Article Name: PUF60 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP40759_T100
Supplier Catalog Number: ARP40759_T100
Alternative Catalog Number: ASB-ARP40759_T100-25UL,ASB-ARP40759_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PUF60
Alternative Names: FIR, VRJS, RoBPI, SIAHBP1
PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 60 kDa
NCBI: 22827
UniProt: Q9UHX1-2
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-PUF60 Antibody
Catalog Number: ARP40759
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
WB Suggested Anti-PUF60 Antibody
Titration: 1.25ug/ml
Positive Control: 293T cells lysate
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 0.2 ug/mL of the antibody was used in this experiment. Recommended dilution is 0.2 ug/mL to 1 ug/mL for this antibody.
PUF60 antibody - C-terminal region (ARP40759_T100) in Human 293T using Western Blot