NXF3 Antibody - C-terminal region
Catalog Number:
ASB-ARP40875_T100
- Images (4)
| Article Name: | NXF3 Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-ARP40875_T100 |
| Supplier Catalog Number: | ARP40875_T100 |
| Alternative Catalog Number: | ASB-ARP40875_T100-25UL,ASB-ARP40875_T100-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human NXF3 |
| NXF3 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF3 has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. |
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Rabbit Anti-NXF3 Antibody Catalog Number: ARP40875 Paraffin Embedded Tissue: Human Heart Cellular Data: Myocardial cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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Rabbit Anti-NXF3 Antibody Catalog Number: ARP40875 Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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WB Suggested Anti-NXF3 Antibody Titration: 1.25ug/ml Positive Control: RPMI 8226 cell lysateNXF3 is supported by BioGPS gene expression data to be expressed in RPMI 8226 |
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NXF3 antibody - C-terminal region (ARP40875_T100) in Human RPMI 8226 using Western Blot |
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