TNRC6A Antibody - N-terminal region

Catalog Number: ASB-ARP40956_P050
Article Name: TNRC6A Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP40956_P050
Supplier Catalog Number: ARP40956_P050
Alternative Catalog Number: ASB-ARP40956_P050-25UL,ASB-ARP40956_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Canine, Equine, Human, Mouse
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TNRC6A
Alternative Names: GW1, FAME6, GW182, TNRC6, CAGH26
TNRC6A is a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 210kDa
NCBI: 27327
UniProt: Q8NDV7
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 6-18% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Protein is modified by phosphorylation. Peptide is contained within isoforms of 210 kDa, 205 and 203 kDa.
WB Suggested Anti-TNRC6A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysate
TNRC6A antibody - N-terminal region (ARP40956_P050) in Human MCF-7 using Western Blot