HERC6 Antibody - N-terminal region

Catalog Number: ASB-ARP43237_P050
Article Name: HERC6 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP43237_P050
Supplier Catalog Number: ARP43237_P050
Alternative Catalog Number: ASB-ARP43237_P050-25UL,ASB-ARP43237_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HERC6
Alternative Names: FLJ20637
HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 115kDa
NCBI: 55008
UniProt: Q8IVU3
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 6-18% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. An isoform containing the peptide sequence is present at 111 kDa.
WB Suggested Anti-HERC6 Antibody Titration: 0.2-1 ug/ml
Positive Control: ACHN cell lysate
HERC6 antibody - N-terminal region (ARP43237_P050) validated by WB using hek293 cell lysate at 1:1000.HERC6 is supported by BioGPS gene expression data to be expressed in HEK293
HERC6 antibody - N-terminal region (ARP43237_P050) in Human ACHN using Western Blot