SLC19A1 Antibody - N-terminal region

Catalog Number: ASB-ARP44167_T100
Article Name: SLC19A1 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP44167_T100
Supplier Catalog Number: ARP44167_T100
Alternative Catalog Number: ASB-ARP44167_T100-25UL,ASB-ARP44167_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Human
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC19A1
Alternative Names: RFC, CHMD, FOLT, IFC1, REFC, RFC1, hRFC, IFC-1, MEGAF, RFT-1, hSLC19A1
Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. SLC19A1 plays a role in maintaining intracellular concentrations of folate.Transport of folate compounds into mammalian cells can occur via receptor-mediated (see MIM 136430) or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.[supplied by OMIM].
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 65 kDa
NCBI: 6573
UniProt: P41440
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human kidney
WB Suggested Anti-SLC19A1 Antibody Titration: 5.0ug/ml
Positive Control: Jurkat cell lysateSLC19A1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. Recommended dilution is 1-3 ug/mL for this antibody.
Western Blot