PTCH1 Antibody - C-terminal region

Catalog Number: ASB-ARP44249_P050
Article Name: PTCH1 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP44249_P050
Supplier Catalog Number: ARP44249_P050
Alternative Catalog Number: ASB-ARP44249_P050-25UL,ASB-ARP44249_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PTCH1
Alternative Names: PTC, BCNS, PTC1, PTCH, NBCCS
PTCH1 is a member of the patched gene family. The protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. It functions as a tumor suppressor. Mutations of its gene have been associated with nevoid basal cell carcinoma syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 37kDa
NCBI: 5727
UniProt: Q6TKP8
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Kidney
Rabbit Anti-PTCH1 Antibody
Catalog Number: ARP44249_P050
Formalin Fixed Paraffin Embedded Tissue: Human Testis Tissue
Observed Staining: Plasma membrane
Primary Antibody Concentration: 1:600
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-PTCH1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate
PTCH1 antibody - C-terminal region (ARP44249_P050) in Human Jurkat using Western Blot