TGFBR2 Antibody - N-terminal region
Catalog Number:
ASB-ARP44743_T100
- Images (4)
| Article Name: | TGFBR2 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP44743_T100 |
| Supplier Catalog Number: | ARP44743_T100 |
| Alternative Catalog Number: | ASB-ARP44743_T100-25UL,ASB-ARP44743_T100-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Goat, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human TGFBR2 |
| Alternative Names: | AAT3, FAA3, LDS2, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TBRII, TBR-ii, TGFR-2, TGFbeta-RII |
| TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in its gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors.This gene is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It encodes a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein and binds TGF-beta. This receptor/ligand complex phosphorylates proteins which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
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WB Suggested Anti-TGFBR2 Antibody Titration: 5.0ug/ml Positive Control: HepG2 cell lysateTGFBR2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells |
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Host: Mouse Target Name: TGFBR2 Sample Tissue: Mouse Spleen Antibody Dilution: 1ug/ml |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 5 ug/mL of the antibody was used in this experiment. Isoforms containing the peptide sequence are present at 50 kDa and 32 kDa. |
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TGFBR2 antibody - N-terminal region (ARP44743_T100) in Human HepG2 using Western Blot |
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