NRCAM Antibody - N-terminal region

Catalog Number: ASB-ARP44833_T100
Article Name: NRCAM Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP44833_T100
Supplier Catalog Number: ARP44833_T100
Alternative Catalog Number: ASB-ARP44833_T100-25UL,ASB-ARP44833_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NRCAM
Alternative Names: KIAA0343, MGC138845, MGC138846
Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. NRCAM is a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM may also play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of its gene have been associated with autism and addiction vulnerability.Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 141kDa
NCBI: 4897
UniProt: Q92823
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human kidney
WB Suggested Anti-NRCAM Antibody Titration: 2.5ug/ml
Positive Control: HepG2 cell lysate
NRCAM antibody - N-terminal region (ARP44833_T100) in Human HepG2 using Western Blot