ENPP2 Antibody - N-terminal region

Catalog Number: ASB-ARP44907_P050
Article Name: ENPP2 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP44907_P050
Supplier Catalog Number: ARP44907_P050
Alternative Catalog Number: ASB-ARP44907_P050-25UL,ASB-ARP44907_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ENPP2
Alternative Names: ATX, NPP2, ATX-X, PDNP2, LysoPLD, AUTOTAXIN, PD-IALPHA
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5 end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 99 kDa
NCBI: 5168
UniProt: Q13822
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
25 ug of the indicated Human whole cell extracts was loaded onto a 6-18% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. The peptide sequence is present in isoforms of 105 and 102 kDa, and the protein is processed to a 95 kDa mature form. The protein may be modified by glycosylation.
WB Suggested Anti-ENPP2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: COLO205 cell lysate
ENPP2 antibody - N-terminal region (ARP44907_P050) in Human COLO205 using Western Blot