SPPL2B Antibody - N-terminal region

Catalog Number: ASB-ARP44989_P050
Article Name: SPPL2B Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP44989_P050
Supplier Catalog Number: ARP44989_P050
Alternative Catalog Number: ASB-ARP44989_P050-25UL,ASB-ARP44989_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPPL2B
Alternative Names: IMP4, PSH4, PSL1, IMP-4
SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 56kDa
NCBI: 56928
UniProt: Q8TCT7-4
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human kidney
WB Suggested Anti-SPPL2B Antibody Titration: 1 ug/ml
Positive Control: Jurkat cell lysateSPPL2B is supported by BioGPS gene expression data to be expressed in Jurkat
SPPL2B antibody - N-terminal region (ARP44989_P050) in Human Jurkat using Western Blot