ACVR2B Antibody - middle region
Catalog Number:
ASB-ARP45042_P050
- Images (3)
| Article Name: | ACVR2B Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP45042_P050 |
| Supplier Catalog Number: | ARP45042_P050 |
| Alternative Catalog Number: | ASB-ARP45042_P050-25UL,ASB-ARP45042_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human ACVR2B |
| Alternative Names: | HTX4, ACTRIIB, ActR-IIB |
| Activin receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. ACVR2B is activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. |
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WB Suggested Anti-ACVR2B Antibody Titration: 0.2-1 ug/ml Positive Control: OVCAR-3 cell lysate |
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Host: Mouse Target Name: ACVR2B Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml |
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ACVR2B antibody - middle region (ARP45042_P050) in Human OVCAR-3 using Western Blot |
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