CDH3 Antibody - N-terminal region

Catalog Number: ASB-ARP45170_T100
Article Name: CDH3 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP45170_T100
Supplier Catalog Number: ARP45170_T100
Alternative Catalog Number: ASB-ARP45170_T100-25UL,ASB-ARP45170_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CDH3
Alternative Names: CDHP, HJMD, PCAD
CDH3 is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Its gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in its gene have been associated with congential hypotrichosis with juvenile macular dystrophy.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 91kDa
NCBI: 1001
UniProt: P22223
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human kidney
WB Suggested Anti-CDH3 Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate
CDH3 antibody - N-terminal region (ARP45170_T100) in Human HepG2 using Western Blot