MTHFD2 Antibody - N-terminal region

Catalog Number: ASB-ARP46038_T100
Article Name: MTHFD2 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP46038_T100
Supplier Catalog Number: ARP46038_T100
Alternative Catalog Number: ASB-ARP46038_T100-25UL,ASB-ARP46038_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MTHFD2
Alternative Names: NMDMC
MTHFD2 is a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD.This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in multiple transcripts encoding different isoforms. This gene has a pseudogene on chromosome 7.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 27 kDa, 38 kDa
NCBI: 10797
UniProt: P13995
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-MTHFD2 Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. Isoforms 1 (38 kDa) and Isoform 2 (27 kDa) can be recognized with this antibody.
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