CENPA Antibody - N-terminal region

Catalog Number: ASB-ARP46040_T100
Article Name: CENPA Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP46040_T100
Supplier Catalog Number: ARP46040_T100
Alternative Catalog Number: ASB-ARP46040_T100-25UL,ASB-ARP46040_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Human, Mouse, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CENPA
Alternative Names: CenH3, CENP-A
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA is a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 16kDa
NCBI: 1058
UniProt: P49450
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human Skin
WB Suggested Anti-CENPA Antibody Titration: 1.25ug/ml
Positive Control: Jurkat cell lysateCENPA is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
CENPA antibody - N-terminal region (ARP46040_T100) in Human Jurkat using Western Blot