Bovine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human LMNB2
Alternative Names:
EPM9, LMN2, LAMB2, MCPH27
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. LMNB2 is one of the two B type proteins, B2.The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Researcher: Dr. David Razafsky, Washington University in Saint Louis Application: IHC Species + Tissue/Cell type: Mouse C2C12 cells Primary antibody dilution: 1:500 Secondary antibody: Goat anti-rabbit-Alexa Fluor 488 Secondary antibody dilution: 1:500
WB Suggested Anti-LMNB2 Antibody Titration: 0.2-1 ug/ml Positive Control: Jurkat cell lysateLMNB2 is supported by BioGPS gene expression data to be expressed in Jurkat
LMNB2 antibody - N-terminal region (ARP46356_P050) in Human Jurkat using Western Blot
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