OSMR Antibody - middle region

Catalog Number: ASB-ARP46396_P050
Article Name: OSMR Antibody - middle region
Biozol Catalog Number: ASB-ARP46396_P050
Supplier Catalog Number: ARP46396_P050
Alternative Catalog Number: ASB-ARP46396_P050-25UL,ASB-ARP46396_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Canine, Equine, Guinea pig, Human, Rabbit
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human OSMR
Alternative Names: OSMRB, PLCA1, IL-31RB, OSMRbeta, IL-31R-beta
Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 110kDa
NCBI: 9180
UniProt: Q99650
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-OSMR Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysate
Host: Rabbit
Target: OSMR
Positive control (+): Human Lung Tumor (T-LU)
Negative control (-): Human Liver Tumor (T-LI)
Antibody concentration: 3ug/ml
OSMR antibody - middle region (ARP46396_P050) in Human 721_B using Western Blot