ATP6V0A1 Antibody - N-terminal region
Catalog Number:
ASB-ARP46581_P050
- Images (3)
| Article Name: | ATP6V0A1 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP46581_P050 |
| Supplier Catalog Number: | ARP46581_P050 |
| Alternative Catalog Number: | ASB-ARP46581_P050-25UL,ASB-ARP46581_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V0A1 |
| Alternative Names: | a1, Stv1, VPP1, Vph1, ATP6N1, ATP6N1A |
| ATP6V0A1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. ATP6V0A1 is one of three A subunit proteins and it is associated with clathrin-coated vesicles. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c, c, and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. The occurrence of splice variants encoding different protein products has been reported, but the full-length natures of these transcripts have not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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WB Suggested Anti-ATP6V0A1 Antibody Titration: 0.2-1 ug/ml Positive Control: Hela cell lysate |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. Canonical isoform for this protein is 96 kDa, but there are dozens of isoforms with small size differences that contain the peptide sequence. These samples seem to express an 87 kDa isoform 16. |
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