DCC Antibody - middle region
Catalog Number:
ASB-ARP46583_P050
- Images (3)
| Article Name: | DCC Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP46583_P050 |
| Supplier Catalog Number: | ARP46583_P050 |
| Alternative Catalog Number: | ASB-ARP46583_P050-25UL,ASB-ARP46583_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human DCC |
| Alternative Names: | CRC18, CRCR1, MRMV1, HGPPS2, IGDCC1, NTN1R1 |
| This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. |
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WB Suggested Anti-DCC Antibody Titration: 0.2-1 ug/ml Positive Control: ACHN cell lysate |
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Host: Rabbit Target Name: DCC Sample Tissue: Human OVCAR-3 Whole Cell Antibody Dilution: 3ug/ml |
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DCC antibody - middle region (ARP46583_P050) in Human ACHN using Western Blot |
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