NAGPA Antibody - N-terminal region
Catalog Number:
ASB-ARP47241_P050
- Images (3)
| Article Name: | NAGPA Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP47241_P050 |
| Supplier Catalog Number: | ARP47241_P050 |
| Alternative Catalog Number: | ASB-ARP47241_P050-25UL,ASB-ARP47241_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N-terminal region of Human NAGPA |
| Alternative Names: | UCE, APAA |
| Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as uncovering enzyme or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. This reaction most likely occurs in the trans-Golgi network. This enzyme functions as a homotetramer of two disulfide-linked homodimers. In addition to having an N-terminal signal peptide, the proteins C-terminus contains multiple signals for trafficking it between lysosomes, the plasma membrane, and trans-Golgi network. |
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Host: Rabbit Target Name: NAGPA Sample Type: OVCAR-3 Whole Cell lysates Antibody Dilution: 1.0ug/ml |
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Host: Rabbit Target Name: NAGPA Sample Tissue: Human HT1080 Whole Cell Antibody Dilution: 3ug/ml |
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NAGPA Antibody - N-terminal region (ARP47241_P050) in Human OVCAR-3 using Western Blot |
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