ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human kidney
WB Suggested Anti-ST14 Antibody Titration: 0.25ug/ml Positive Control: DLD1 cell lysateST14 is strongly supported by BioGPS gene expression data to be expressed in Human DLD1 cells
ST14 antibody - C-terminal region (ARP48056_P050) in Human DLD1 using Western Blot
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