AKT1S1 Antibody - C-terminal region

Catalog Number: ASB-ARP48061_P050
Article Name: AKT1S1 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP48061_P050
Supplier Catalog Number: ARP48061_P050
Alternative Catalog Number: ASB-ARP48061_P050-25UL,ASB-ARP48061_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AKT1S1
Alternative Names: Lobe, PRAS40
AKT1S1 may play an important role in phosphatidylinositol 3-kinase (PI3K)-AKT1 survival signaling. It is the substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. AKT1S1 may also play a role in nerve growth factor-mediated neuroprotection.AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM].
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 27kDa
NCBI: 84335
UniProt: Q96B36
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-AKT1S1 Antibody
Catalog Number: ARP48061_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic in endothelial cells in blood vessels
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-AKT1S1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 293T cell lysate
AKT1S1 antibody - C-terminal region (ARP48061_P050) in Human 293T using Western Blot