PAX8 Antibody - N-terminal region

Catalog Number: ASB-ARP48088_P050
Article Name: PAX8 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP48088_P050
Supplier Catalog Number: ARP48088_P050
Alternative Catalog Number: ASB-ARP48088_P050-25UL,ASB-ARP48088_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAX8
Conjugation: Unconjugated
PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in its gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 48kDa
NCBI: 7849
UniProt: Q06710
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-PAX8 Antibody
Catalog Number: ARP48088_P050
Formalin Fixed Paraffin Embedded Tissue: Human Thyroid Tissue
Observed Staining: Nucleus in follicular cells
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-PAX8 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
PAX8 antibody - N-terminal region (ARP48088_P050) in Human HepG2 using Western Blot