TRDMT1 Antibody - N-terminal region

Catalog Number: ASB-ARP48627_P050
Article Name: TRDMT1 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP48627_P050
Supplier Catalog Number: ARP48627_P050
Alternative Catalog Number: ASB-ARP48627_P050-25UL,ASB-ARP48627_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRDMT1
Alternative Names: DMNT2, DNMT2, PUMET, RNMT1, MHSAIIP
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. TRDMT1 is a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome.CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 45 kDa
NCBI: 1787
UniProt: O14717
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-TRDMT1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Muscle
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment.
TRDMT1 antibody - N-terminal region (ARP48627_P050) in Human Muscle using Western Blot