OGT Antibody - N-terminal region

Catalog Number: ASB-ARP49154_P050
Article Name: OGT Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP49154_P050
Supplier Catalog Number: ARP49154_P050
Alternative Catalog Number: ASB-ARP49154_P050-25UL,ASB-ARP49154_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human OGT
Alternative Names: OGT1, HRNT1, MRX106, HINCUT-1, O-GLCNAC
OGT catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 117kDa
NCBI: 8473
UniProt: O15294
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-OGT Antibody
Catalog Number: ARP49154_P050
Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue
Observed Staining: Cytoplasmic in processes of pinealocytes and endothelial cells in blood vessels
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1/600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
Host: Rabbit
Target Name: OGT
Sample Type: 721_B Whole Cell lysates
Antibody Dilution: 1.0ug/mlOGT is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
OGT antibody - N-terminal region (ARP49154_P050) in Human 721_B using Western Blot