PCDHGC4 Antibody - N-terminal region
Catalog Number:
ASB-ARP49389_P050
- Images (3)
| Article Name: | PCDHGC4 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP49389_P050 |
| Supplier Catalog Number: | ARP49389_P050 |
| Alternative Catalog Number: | ASB-ARP49389_P050-25UL,ASB-ARP49389_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Equine, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHGC4 |
| Alternative Names: | PCDH-GAMMA-C4 |
| PCDHGC4 is a single-pass type I membrane protein. It contains 6 cadherin domains.PCDHGC4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. |
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PCDHGC4 antibody - N-terminal region (ARP49389_P050) Catalog Number: ARP49389_P050 Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue Observed Staining: Cytoplasm of pneumocytes Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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WB Suggested Anti-PCDHGC4 Antibody Titration: 0.2-1 ug/ml Positive Control: 293T cell lysate |
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PCDHGC4 antibody - N-terminal region (ARP49389_P050) in Human 293T using Western Blot |
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