LRRC8A Antibody - N-terminal region

Catalog Number: ASB-ARP49452_P050
Article Name: LRRC8A Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP49452_P050
Supplier Catalog Number: ARP49452_P050
Alternative Catalog Number: ASB-ARP49452_P050-25UL,ASB-ARP49452_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LRRC8A
Alternative Names: AGM5, LRRC8, SWELL1, HsLRRC8A
LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 94kDa
NCBI: 56262
UniProt: Q8IWT6
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-LRRC8A Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate
Host: Rabbit
Target Name: LRRC8A
Sample Tissue: Human HepG2
Antibody Dilution: 1.0ug/ml
LRRC8A antibody - N-terminal region (ARP49452_P050) in Human HepG2 using Western Blot