Bovine, Canine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human TUSC4
Alternative Names:
NPR2, NPR2L, TUSC4, FFEVF2
TUSC4 suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. TUSC4 down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. TUSC4 may act as a tumor suppressor. TUSC4 suppresses cell growth and enhanced sensitivity to various anticancer drugs.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-TUSC4 Antibody Catalog Number: ARP50539_P050 Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver Observed Staining: Cytoplasm in hepatocytes, moderate signal, very low tissue distribution Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 a€'' 2.0 sec Protocol located in Reviews and Data.
WB Suggested Anti-TUSC4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: OVCAR-3 cell lysateNPRL2 is supported by BioGPS gene expression data to be expressed in OVCAR3
TUSC4 antibody - N-terminal region (ARP50539_P050) in Human OVCAR-3 using Western Blot
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